Accession Number : ADB269339


Title :   Resources for Precision Analysis of Human Breast Cancer


Descriptive Note : Annual rept. 15 Jul 1999-15 Jul 2000


Corporate Author : MANITOBA UNIV WINNIPEG


Personal Author(s) : Watson, Peter


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/b269339.pdf


Report Date : Aug 2000


Pagination or Media Count : 80


Abstract : This US Army academic award guarantees ongoing protection and a balance of 75/25% of my time for research/clinical activities. This ensures my continued active contribution to breast cancer research through specific projects underway in my laboratory as well as through efforts to maintain and improve on resources that offer appropriately processed, relevant and pathologically defined tissue samples to other investigators. This award has allowed the PI to 1) continue to advance research projects that are currently ongoing in the laboratory focusing on the role of the psoriasin and lumican genes, the identification of additional novel genes associated with progression of pre-invasive DCIS to invasive disease, and alteration of ER and associated proteins that may affect response to endocrine therapies, and 2) continue to direct the NCIC-Manitoba Breast Tumor Bank and offer clinical pathology expertise and advice to many investigators who seek access to appropriate tissues to test their ideas in conjunction with tissues associated with NCIC-clinical trial datasets, and tissues comprising pre-neoplastic and pre-invasive lesions.


Descriptors :   *CLINICAL MEDICINE , *GENES , *MEDICAL RESEARCH , *BREAST CANCER , TISSUES(BIOLOGY) , PROTEINS , DISEASES , THERAPY , PATHOLOGY , RESPONSE(BIOLOGY) , ENDOCRINE GLANDS , ENDOCRINOLOGY


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE