Accession Number : ADA633554


Title :   Identification of the srtC1 Transcription Start Site and Catalytically Essential Residues Required for Actinomyces oris T14V SrtC1 Activity


Descriptive Note : Journal article


Corporate Author : ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX


Personal Author(s) : Chen, Ping ; Leung, Kai P


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a633554.pdf


Report Date : 27 Jul 2011


Pagination or Media Count : 9


Abstract : In Actinomyces oris T14V, sortase SrtC1 mediates the assembly of type 1 fimbriae. We analyzed the effects of the conserved residues (H184, H204, F213, Y236, L263, T265, C266 and R275) on the SrtC1 activity by site directed mutagenesis.


Descriptors :   *ACTINOMYCES , CLINICAL MEDICINE , DEOXYRIBONUCLEIC ACIDS , GROWTH(PHYSIOLOGY) , IMMUNOLOGY , PLASMIDS , STRAINS(BIOLOGY) , TRANSCRIPTION(GENETICS)


Subject Categories : Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE