Accession Number : ADA626598


Title :   Molecular & Genetic Investigation of Tau in Chronic Traumatic Encephalopathy


Descriptive Note : Annual rept. 30 Sep 2014-29 Sep 2015


Corporate Author : ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NEW YORK


Personal Author(s) : Crary, John F


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a626598.pdf


Report Date : Oct 2015


Pagination or Media Count : 4


Abstract : Repetitive mild TBI leads to chronic traumatic encephalopathy (CTE), but the underlying molecular changes remain unclear. Here, biochemical and genetic studies that deepen our understanding of the pathogenesis of CTE will be performed, facilitating diagnosis and therapeutic development. This award has been in the transfer process from Columbia University to the Icahn School of Medicine at Mount Sinai until 10/28/2015, thus no funds have been available to initiate the project. Now that funds are available, work will commence.


Descriptors :   *DIAGNOSIS(MEDICINE) , *GENETICS , *TRAUMATIC BRAIN INJURIES , BIOCHEMISTRY , BRAIN FUNCTION IMPAIRMENT , DEGENERATION(PHYSIOLOGY) , ENCEPHALITIS , GENE EXPRESSION , MOLECULAR DYNAMICS , NEUROBIOLOGY , PATHOGENESIS , PATIENTS , PROTEINS , THERAPY


Subject Categories : Biochemistry
      Genetic Engineering and Molecular Biology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE