Accession Number : ADA621838


Title :   Study of the Neurophysiology of Central Fatigue


Descriptive Note : Final rept. 1 Jul 2010-30 Jun 2014


Corporate Author : COLORADO UNIV AT DENVER


Personal Author(s) : Kluger, Benzi ; Ding, Mingzhou ; Rojas, Donald ; Krupp, Lauren ; Enoka, Roger


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a621838.pdf


Report Date : 05 Nov 2014


Pagination or Media Count : 7


Abstract : Specific Aims: 1) To identify and characterize the functional neuroanatomic networks most strongly correlated with objective cognitive fatigue using event related potentials (ERPs). 2) To determine the neurophysiologic mechanisms underlying objective cognitive fatigue using the variable signal plus ongoing activity (VSPOA) model. 3) To investigate the relationship of GABAergic and glutamatergic neural transmission to objective cognitive fatigue and network pathology.


Descriptors :   *FATIGUE(PHYSIOLOGY) , *NERVE TRANSMISSION , *NEUROPHYSIOLOGY , BEHAVIOR , COGNITION , CORRELATION , INFORMATION PROCESSING , NETWORK ARCHITECTURE , NEURAL NETS , PATHOPHYSIOLOGY , PERFORMANCE(HUMAN) , PSYCHOMOTOR FUNCTION , REACTION TIME , RESPONSE(BIOLOGY) , SIGNAL PROCESSING


Subject Categories : Psychology
      Medicine and Medical Research
      Stress Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE