Accession Number : ADA621297


Title :   Temporal Progression of Visual Injury from Blast Exposure


Descriptive Note : Annual rept. 1 Sep 2012-31 Aug 2013


Corporate Author : UTAH UNIV SALT LAKE CITY


Personal Author(s) : Coats, Brittany ; Shedd, Daniel


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a621297.pdf


Report Date : Sep 2013


Pagination or Media Count : 18


Abstract : The purpose of this grant is to investigate the temporal progression of eye injury from blast exposure and identify early predictors of visual dysfunction. We propose to accomplish this by first identifying the probability of military personnel developing visual system injury after blast exposure, and determining the time point after blast exposure that visual system injury becomes identifiable. Next, we propose to systematically evaluate the time course of visual system injury from blast exposure using our existing rat model for blast traumatic brain injury. From the studies performed in the previous year, we have found that low-level blast exposure (225 kPa) in rats appears to result in a general decrease in visual acuity without any signs of stress or pain in the animals. Scleral hemorrhage was observed upon gross exam.


Descriptors :   *EYE , *TRAUMA , *WOUNDS AND INJURIES , BIOMECHANICS , BLAST , DIAGNOSIS(MEDICINE) , HEMORRHAGE , PREDICTIONS , RATS , SIGNS AND SYMPTOMS , VISUAL ACUITY


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE