Accession Number : ADA620325


Title :   Validating Biomarkers for PTSD


Descriptive Note : Annual rept. 1 Apr 2014-31 Mar 2015


Corporate Author : NEW YORK UNIV NY


Personal Author(s) : Marmar, Charles R


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a620325.pdf


Report Date : Apr 2015


Pagination or Media Count : 23


Abstract : Validating markers is particularly important, as few biomarkers for PTSD studies have replicated findings following the test results and even fewer have examined the stability of biological markers longitudinally. Those longitudinal studies which have been conducted in PTSD suggest that neural activity may change with symptom trajectories. Longitudinal stress research suggests that other biomarkers may change over time, including gene expression and neuroendocrine functioning. One of the aims of the proposed study is to fill this gap in knowledge, by re-evaluating 70 participants from our original sample (35 PTSD+ and 35 PTSD-) to confirm the stability of biomarkers.


Descriptors :   *MARKERS , *POST TRAUMATIC STRESS DISORDER , ENDOCRINE GLANDS , GENES , MENTAL DISORDERS , MENTAL HEALTH , NEUROCHEMISTRY , NEUROLOGY , STABILITY , STRESS(PSYCHOLOGY) , TEST AND EVALUATION , TRACER STUDIES , TRAUMA , VETERANS(MILITARY PERSONNEL)


Subject Categories : Psychology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE