Accession Number : ADA617664


Title :   BioComponent Robots


Descriptive Note : Final rept. 5 Feb 2011-4 Feb 2015


Corporate Author : TUFTS UNIV MEDFORD MA


Personal Author(s) : Kaplan, David ; Trimmer, Barry


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a617664.pdf


Report Date : 13 Feb 2014


Pagination or Media Count : 17


Abstract : The project goal was to exploit insect cell culture and tissue engineering approaches to generate biological actuators, utilizing the unique hardiness and longevity of insect cell sources for device applications for robotics. In contrast to mammalian cells and tissues, insect cells survive with minimal assistance over long periods of time and are immune to routine environmental perturbations. The project focused on 3 tasks: 1) cell-based actuators and biostability, 2) energy storage and conversion, and 3) tissue engineering. All phases of the project required new methods in order to move forward and significant progress was made on the three tasks. Cell sources from insects were isolated, cultivated, grown to confluence and beating muscle assemblies were generated and demonstrated forces comparable to bioengineered mammalian muscle systems. These systems were grown for at least three months without feeding or special handling. Metabolic studies characterized the carbon fluxes from the cells to provide insight into the role of adipose reserves in supporting cell functions. Studies related to anchoring the actuators and organizing multi-actuator systems, including the use of extracellular matrix components from the caterpillar body wall, were studied for generating functional assemblies. The project was terminated early due to funding constraints.


Descriptors :   *FIBROIN , *TISSUE CULTURE CELLS , ACTUATORS , ELASTOMERS , EXPERIMENTAL DESIGN , INSECTS , MUSCLE FIBERS , ROBOTICS , SILK , THIN FILMS


Subject Categories : Anatomy and Physiology
      Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE