Accession Number : ADA617417


Title :   Targeting of the MUC1-C Oncoprotein in Colitis-Associated Colorectal Cancer


Descriptive Note : Final rept. 14 Aug 2012-14 Aug 2014


Corporate Author : DANA-FARBER CANCER INST BOSTON MA


Personal Author(s) : Kufe, Donald W


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a617417.pdf


Report Date : Nov 2014


Pagination or Media Count : 17


Abstract : Inflammatory bowel disease (IBD) is associated with the development of colorectal cancer. however, little is known about the mechanisms responsible for the progression of IBD to this malignancy. Our idea is that a better understanding of how IBD progresses to colorectal cancer will provide new insights for drug development against these malignancies.


Descriptors :   *COLON CANCER , DRUGS , INFLAMMATION , RESPONSE(BIOLOGY)


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE