Accession Number : ADA616319


Title :   Self-Assembly of Large-Scale Shape-Controlled DNA Nano-Structures


Descriptive Note : Final rept. 1 Aug 2011-31 Jul 2014


Corporate Author : PRESIDENT AND FELLOWS OF HARVARD COLL CAMBRIDGE MA OFFICE OF SPONSORED RESEARCH


Personal Author(s) : Yin, Peng


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a616319.pdf


Report Date : 16 Dec 2014


Pagination or Media Count : 112


Abstract : We proposed to develop a methodology by using short synthetic DNA strands to build complex DNA nano-structures. In such a methodology, each short synthetic DNA strand, called DNA brick, is designed as a modular building block to assemble large structure with nanometer scale geometry control. We are using the methodology to build a variety of complex nano-structures, including 1D, 2D, 3D discrete structures and extended crystals. We are also developing a number of real world applications based on these novel structures. The successful development of this modular nano construction methodology and the associated real world applications will have transformative impact.


Descriptors :   *DEOXYRIBONUCLEIC ACIDS , CRYSTALS , NANOSTRUCTURES , NANOTECHNOLOGY , TWO DIMENSIONAL


Subject Categories : Biochemistry
      Genetic Engineering and Molecular Biology
      Physical Chemistry


Distribution Statement : APPROVED FOR PUBLIC RELEASE