Accession Number : ADA614618


Title :   Evaluation of the Specificity and Sensitivity of a Potential Rapid Influenza Screening System


Descriptive Note : Journal article


Corporate Author : ARMY INST OF SURGICAL RESEARCH FORT SAM HOUSTON TX


Personal Author(s) : Perez, Luis E ; Merrill, Gerald A ; DeLorenzo, Robert A ; Schoenfeld, Thomas W ; Vats, Abhay ; Moser, Michael J


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a614618.pdf


Report Date : Jan 2013


Pagination or Media Count : 5


Abstract : Influenza remains a serious worldwide health threat with numerous deaths attributed to influenza-related complications. It is likely that transmission of influenza and both the morbidity and mortality of influenza could be reduced if inexpensive but reliable influenza screening assays were more available to the general public or local medical treatment facilities. This report provides the initial evaluation of a pilot system designed by Lucigen Corp. (Middleton, WI, USA) as a potential rapid near point-of-care screening system for influenza A and influenza B. The evaluation of specificity and sensitivity was conducted on stored nasal swab samples collected from emergency department patients presenting with influenza-like symptoms at a large military academic hospital and on de-identified nasal swabs and isolated RNA from a local epidemiology laboratory. The gold standard for assessment of specificity and sensitivity was the Luminex Respiratory Viral Panel.


Descriptors :   *INFLUENZA VIRUS , *MEDICAL SCREENING , ASSAYING , INFLUENZA , SENSITIVITY , SIGNS AND SYMPTOMS


Subject Categories : Medicine and Medical Research
      Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE