Accession Number : ADA613227


Title :   Absorbable Antimicrobial Battlefield Hemostat


Descriptive Note : Final rept. 19 September 2011- 18 March 2013


Corporate Author : NORTH DAKOTA UNIV GRAND FORKS


Personal Author(s) : Zhao, Julia


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a613227.pdf


Report Date : Apr 2013


Pagination or Media Count : 25


Abstract : Uncontrolled bleeding on the battlefield results in a 90% mortality rate within the first hour. Unfortunately, in combat operations, such medical intervention within the golden hour is not always possible, and 50% of battlefield deaths are still due to traumatic hemorrhage. The injury and continued bleeding of the compromised patient needs novel hemostats. A potential solution to this problem is an effective battlefield hemostat that can be resorbed by the body without the requirement for device removal. The object of this proposal is to develop nanomaterial hemostat based on silica nanofibers. Nanosys Inc. and University of North Dakota (UND) have built some platforms to move to the next step by improving the antimicrobial efficacy of the dressing and subsequently, improving its resorptive properties ensuring that this dressing becomes a complete solution for DoD. Our research results suggest that the nanofibers can be resorbed but we would likely need to limit the amount of material left in for effective resorption. The silicon nanofibers did not cause any major irritation, toxicity, and/or inflammatory response, and may represent new formats of hemostat materials that can quickly and effectively stop bleeding at the battlefield.


Descriptors :   *HEMORRHAGE , ANTIMICROBIAL AGENTS , DRESSINGS , FIBERS , WOUNDS AND INJURIES


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE