Accession Number : ADA612616


Title :   Cavitation Induced Structural and Neural Damage in Live Brain Tissue Slices: Relevance to TBI


Descriptive Note : Final rept. 1 Sep 2010-31 Aug 2014


Corporate Author : FLORIDA UNIV GAINESVILLE DEPT OF MECHANICAL AND AEROSPACE ENGINEERING


Personal Author(s) : Subhash, Ghatu


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a612616.pdf


Report Date : 29 Sep 2014


Pagination or Media Count : 45


Abstract : Cavitation-induced shock wave, as might occur in the head during exposure to blast waves, was investigated as a possible damage mechanism for soft brain tissues. A novel experimental scheme was developed to visualize and control single bubble cavitation and its collapse, and the influence of this process on a nearby tissue surrogate was investigated. The experiment utilized a Hopkinson pressure bar system which transmits a simulated blast pressure wave (with over and under pressure components) to a fluid-filled test chamber implanted with a seed gas bubble.


Descriptors :   *BRAIN , *CAVITATION , *TISSUES(BIOLOGY) , *TRAUMATIC BRAIN INJURIES , CEREBROSPINAL FLUID , DAMAGE , SAMPLING , SHOCK WAVES


Subject Categories : Biology
      Anatomy and Physiology
      Medicine and Medical Research
      Fluid Mechanics


Distribution Statement : APPROVED FOR PUBLIC RELEASE