Accession Number : ADA607156


Title :   Comprehensive Clinical Phenotyping & Genetic Mapping for the Discovery of Autism Susceptibility Genes


Descriptive Note : Final rept. 30 Sep 2009-31 Dec 2012


Corporate Author : NATIONWIDE CHILDREN'S HOSPITAL COLUMBUS OH RESEARCH INST


Personal Author(s) : Herman, Gail E


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a607156.pdf


Report Date : 05 Dec 2012


Pagination or Media Count : 56


Abstract : Autism is the fastest growing developmental disability in the US, costing more than $90 billion/yr, and is, therefore, extremely important to the DoD. According to the Military Times (Robert Dorr, 8/13/11), autism is the most prevalent special-needs issue in military families. Autism spectrum disorders (ASDs) have a frequency of 1/88 in the general population (1) and an estimated frequency of 1/88 in the military (Organization of Autism Research). Affected children display qualitative impairments in social interaction, expressive and receptive language, and the use of symbolic or imaginative play, with an age of onset before 3 years. In addition, many children display restricted, repetitive, and stereotyped patterns of behaviors. Specific military preparedness issues for families with a child with an ASD include the stress of deployments and frequent moves; early retirement or lack of re-enlistment for family concerns; and limited community resources at many smaller bases. ASDs pose a particularly high level of stress for many military families; however, substantial improvements are attainable through collaborative translational research linked to better care.CORA was initiated in 2006 as a collaboration between Wright-Patterson Air Force Base (WPAFB) and Nationwide Children s Hospital (NCH). The primary purpose of CORA is to develop a comprehensive autism registry for genetic and other studies for military and civilian families in central Ohio.


Descriptors :   *CLINICAL MEDICINE , *MENTAL DISORDERS , CHILDREN , DISPLAY SYSTEMS , FAMILY MEMBERS , GENES , GENETIC MAPPING , MILITARY OPERATIONS , OPERATIONAL READINESS , RETIREMENT , SPECTRA , STRESSES


Subject Categories : Psychology


Distribution Statement : APPROVED FOR PUBLIC RELEASE