Accession Number : ADA606443


Title :   Acute Dermal Irritation Study of Six Jet Fuels in New Zealand White Rabbits: Comparison of Four Bio-Based Jet Fuels with Two Petroleum JP-8 Fuels


Descriptive Note : Interim rept. Jun 2013-Jan 2014


Corporate Author : HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE WRIGHT-PATTERSON AFB OH


Personal Author(s) : Sterner, Teresa R ; Hurley, Jonathon M ; Edwards, James T ; Shafer, Linda M ; Mattie, David R


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a606443.pdf


Report Date : Feb 2014


Pagination or Media Count : 65


Abstract : The objective of this study was to determine the irritative potential of two petroleum derived operational jet fuels and four alternative fuels following a single exposure to the skin of New Zealand White rabbits. Operational fuels included two JP-8 formulations: JP-8 containing 21.25 mass percent aromatic components as a baseline control for the study and a second high aromatic (HA) JP-8 containing 28.05 mass percent aromatics for comparison with higher aromatic alternative fuels. The alternative fuels assessed were KiOR hydroprocessed depolymerized cellulosic jet (HDCJ) fuel; ReadiJet fuel produced by Applied Research Associates; Amyris C15 Direct Sugar to Hydrocarbon (DSHC); and Virent Synthetic Aromatic Kerosene (SAK). There were no significant differences in irritation noted between the baseline fuels (JP-8 and HA JP-8) and the four alternate jet fuels; all were slightly irritating when exposed under occluded and semi-occluded conditions, with the exception of ?ReadiJet? which was nonirritating when exposed semi-occluded. It is not expected that normal handling of these fuels would result in increased dermal irritation among airmen.


Descriptors :   *CRUDE OIL , *JET ENGINE FUELS , AROMATIC COMPOUNDS , EXPOSURE(GENERAL) , FORMULATIONS , IRRITATION , KEROSENE , TOXICITY , TOXICOLOGY


Subject Categories : Fuels


Distribution Statement : APPROVED FOR PUBLIC RELEASE