Accession Number : ADA603076


Title :   Twelve-Hour Duration Testing of Cream Formulations of Three Repellents Against Amblyomma americanum


Descriptive Note : Journal article


Corporate Author : ARMY MEDICAL DEPT CENTER AND SCHOOL FORT SAM HOUSTON TX


Personal Author(s) : Carroll, J F ; Benante, J P ; Klun, J A ; White, C E ; Debboun, M ; Pound, J M ; Dheranetra, W


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a603076.pdf


Report Date : Jan 2008


Pagination or Media Count : 9


Abstract : The repellent efficacies of the U.S. military repellent 33% N,N-diethy l-3-methylbenzamide (deet), 10% and 20% (1S, 2 'S) 2-methylpiperidinyl-3-cyclohexene- 1-carboxamide (SS220) and 10% and 20% 1-methyl-propyl-2-(hydroxyethyl)-1-piperidinecarboxylate (Bayrepel) cream formulations on human volunteers against the lone star tick Amblyomma americanum (L.) were evaluated in a simulated forest floor environment over a 12-h testing period. At 2-h intervals, volunteers, with repellent applied in a 5-cm-wide band around each ankle, stood for 5 min in plastic tubs containing leaf litter and 100 host-seeking A. americanum nymphs. Ticks were allowed to remain on a volunteer s feet and ankles for an additional 5 min after the volunteer exited the tub. All repellent formulations provided high levels of protection for the entire 12 h. No ticks crossed 5-cm-wide bands of 20% SS220 and Bayrepel during any challenge, and thus 100% protection was afforded throughout the test. These formulations showed a long lasting efficacy hitherto unknown in tick repellents intended for use on human skin.


Descriptors :   *REPELLENTS , *TICKS , BIOASSAY , FORMULATIONS , HUMANS , LEGS , SKIN(ANATOMY) , TEST AND EVALUATION


Subject Categories : Agricultural Chemistry
      Biology


Distribution Statement : APPROVED FOR PUBLIC RELEASE