Accession Number : ADA601965


Title :   Information Processing and Collective Behavior in a Model Neuronal System


Descriptive Note : Final rept. 15 Jul 2011-31 Dec 2013


Corporate Author : MICHIGAN UNIV REGENTS ANN ARBOR DIV OF RESEARCH DEVELOPMENT AND ADMINISTRATION


Personal Author(s) : Forger, Daniel B


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a601965.pdf


Report Date : 28 Mar 2014


Pagination or Media Count : 27


Abstract : This project used neurons in the suprachiasmatic nucleus to understand information processing and collective behavior. The work is computational, and all work done with mathematical models that have been fit to experimental data. Models simulated up to 20,000 neurons in which internal molecular oscillations, with a period of around a day, are generated. On a fast neuronal timescale, these rhythms are co-ordinated and used to process environmental information. By studying this system, we learn about how multiagent systems can efficiently process environmental signals. Our progress was superb and lead to many key papers in high-impact journals. There was also great interest in our work, and we were called on to additionally explore how similar systems in other tissues (e.g. the heart) or organisms (e.g. the Monarch, which is currently being studied by other AFOSR researchers). This was done in addition to meeting the original goals of the grant.


Descriptors :   *CIRCADIAN RHYTHMS , INFORMATION PROCESSING , MATHEMATICAL MODELS , MULTIAGENT SYSTEMS , NERVE CELLS


Subject Categories : Biochemistry
      Anatomy and Physiology
      Computer Programming and Software


Distribution Statement : APPROVED FOR PUBLIC RELEASE