Accession Number : ADA599898


Title :   Advanced Functional Nanomaterials for Biological Processes


Descriptive Note : Final rept. 24 Sep 2010-23 Oct 2013


Corporate Author : ARKANSAS UNIV AT LITTLE ROCK


Personal Author(s) : Biris, Alexandru S ; Zharov, Vladimir P


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a599898.pdf


Report Date : Jan 2014


Pagination or Media Count : 41


Abstract : During the course of this project, we performed research in the area of tissue engineering/bone regeneration and cancer nanotechnology. The primary focus of the tissue engineering program was to understand the biophysiological activity of the complex multicomponent nanopolymeric scaffolds in goat models for the regeneration of bone tissue and BMP delivery. For the cancer research, we focused on synthesizing highly functional nanomaterials that have both magnetic and spectroscopic properties. They were linked with targeting agents and used for successful Radio-Frequency (RF) driven thermal ablation of cancer cells in vitro. We also designed a platform technology for the accurate delivery of cancer cells in circulation based on a photothermal/photoacoustic approach.


Descriptors :   *CANCER , *TISSUES(BIOLOGY) , ACCURACY , BONES , CIRCULATION , MAGNETIC PROPERTIES , MEDICAL RESEARCH , NANOPARTICLES , PHOTOTHERMAL PROPERTIES , REGENERATION(PHYSIOLOGY)


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE