Accession Number : ADA598372


Title :   Development of Synthetic Spider Silk Fibers for High Performance Applications


Descriptive Note : Final rept. 1 Jun 2010-31 May 2013


Corporate Author : REFACTORED MATERIALS INC SAN FRANCISCO CA


Personal Author(s) : Breslauer, David N


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a598372.pdf


Report Date : 08 Aug 2013


Pagination or Media Count : 24


Abstract : The overall goal of this project is to demonstrate the feasibility of synthetic production of high-performance spider silk fibers for use in next-generation automotives, aerospace, body and vehicle armor, ropes, webbing, and advanced composites. This requires creating a system for producing the protein-based material with sufficient efficiency that, scaled up, would be commercially viable. Using cutting edge techniques in synthetic biology (e.g. gene design and synthesis), we created multiple type and multiple size silk sequences for maximum expression in a scalable, high expression recombinant organism. We created laboratory scale quantities of silk protein feedstock to determine the feasibility of synthetic spider silk production for commercial uses.


Descriptors :   *PRODUCTION , *SILK , *SYNTHETIC BIOLOGY , DEOXYRIBONUCLEIC ACIDS , FERMENTATION , FIBERS , GENES , PROTEINS , PURIFICATION , SPINNING(INDUSTRIAL PROCESSES) , STRAINS(BIOLOGY)


Subject Categories : Genetic Engineering and Molecular Biology
      Textiles
      Mfg & Industrial Eng & Control of Product Sys


Distribution Statement : APPROVED FOR PUBLIC RELEASE