Accession Number : ADA592056


Title :   Nano-engineered Drug Combinations for Breast Cancer Treatment


Descriptive Note : Final rept. 15 May 2011-14 May 2013


Corporate Author : MICHIGAN UNIV ANN ARBOR


Personal Author(s) : Lahann, Joerg


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a592056.pdf


Report Date : Aug 2013


Pagination or Media Count : 15


Abstract : We hypothesis that nanoparticles can increase the efficacy of combination therapies for cancer. The project aims to explore nanoparticle-based transport vehicles for effective delivery of two different cancer drugs. In particular, we aim to use two breast cancer drugs, which enhance each other s efficacy and use them as a model drug pair for the development of novel dual-drug nano-therapeutics. The research to date has been focused on extending existing electrohydrodynamic co-jetting technology in the Lahann lab towards the simultaneous release of two independent small molecule drug surrogates.


Descriptors :   *BREAST CANCER , CHEMOTHERAPY , DRUGS


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE