Accession Number : ADA582846


Title :   Plasma-Enhanced Copolymerization of Amino Acid and Synthetic Monomers


Descriptive Note : Journal article


Corporate Author : GEORGIA INST OF TECH ATLANTA SCHOOL OF MATERIALS SCIENCE AND ENGINEERING


Personal Author(s) : Anderson, Kyle D ; Young, Seth L ; Jiang, Hao ; Jakubiak, Rachel ; Bunning, Timothy J ; Naik, Rajesh R ; Tsukruk, Vladimir V


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a582846.pdf


Report Date : 16 Dec 2011


Pagination or Media Count : 14


Abstract : In this paper we report the use of plasma-enhanced chemical vapor deposition (PECVD) for the simultaneous deposition and copolymerization of an amino acid with other organic and inorganic monomers. We investigate the fundamental effects of plasma-enhanced copolymerization on different material chemistries in stable ultrathin coatings of mixed composition with an amino acid component. This study serves to determine the feasibility of a direct, facile method for integrating biocompatible/active materials into robust polymerized coatings with the ability to plasma copolymerize a biological molecule (L-tyrosine) with different synthetic materials in a dry, one-step process to form ultrathin coatings of mixed composition. This process may lead to a method of interfacing biologic systems with synthetic materials as a way to enhance the biomaterial-tissue interface and preserve biological activity within composite films.


Descriptors :   *AMINO ACIDS , *COPOLYMERIZATION , *MONOMERS , *SYNTHETIC MATERIALS , BIOLOGY , CHEMICAL VAPOR DEPOSITION


Subject Categories : Biochemistry
      Organic Chemistry
      Polymer Chemistry
      Plastics


Distribution Statement : APPROVED FOR PUBLIC RELEASE