Accession Number : ADA573887


Title :   Investigations of Tissue-Level Mechanisms of Primary Blast Injury Through Modeling, Simulation, Neuroimaging and Neuropathological Studies


Descriptive Note : Final rept. 1 Aug 2011-14 Nov 2012


Corporate Author : MASSACHUSETTS INST OF TECH CAMBRIDGE


Personal Author(s) : Radovitzky, R ; Socrate, S ; Taber, K ; Hurley, R ; Moore, David ; Son, Steve ; Chen, Wayne ; Deshler, James ; Subhash, Ghatu ; Bass, Cameron


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a573887.pdf


Report Date : 10 Jul 2012


Pagination or Media Count : 52


Abstract : Traumatic brain injury (TBI) to U.S. soldiers has become one of the most taxing consequences of IED attacks in OEF/OIF. This project has focused on investigations of traumatic injury to the brain caused by the primary effects of blast waves. The project combines clinical, experimental and modeling studies aimed at: (i) elucidating the cell and tissue-level mechanisms of injury produced by the effect of the blast wave, (ii) deriving associated blast injury criteria (metrics and thresholds), (iii) helping to identify and treat returnees suffering from TBI, and (iv) developing blast protection strategies for TBI mitigation.


Descriptors :   *TRAUMATIC BRAIN INJURIES , ARMY PERSONNEL , BLAST WAVES , CELLS(BIOLOGY)


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE