Accession Number : ADA552422


Title :   Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update (Executive Summary)


Descriptive Note : Journal article


Corporate Author : SAN ANTONIO MILITARY MEDICAL CENTER FORT SAM HOUSTON TX


Personal Author(s) : Hospenthal, Duane R ; Murray, Clinton K ; Andersen, Romney C ; Bell, R B ; Calhoun, Jason H ; Cancio, Leopoldo C ; Cho, John M ; Chung, Kevin K ; Clasper, Jon C ; Colyer, Marcus H


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a552422.pdf


Report Date : Aug 2011


Pagination or Media Count : 9


Abstract : Despite advances in resuscitation and surgical management of combat wounds, infection remains a concerning and potentially preventable complication of combat-related injuries. Interventions currently used to prevent these infect ions have not been either clearly defined or subjected to rigorous clinical trials. Current infection prevention measures and wound management practices are derived from retrospective review of wartime experiences, from civilian trauma data and from in Vitro and animal data. This update to the guidelines published in 2008 incorporates evidence that has become available since 2007. These guidelines focus on care provided within hours to days of injury, chiefly within the combat zone to those combat-injured patients with open wounds or burns. New in this update are a consolidation of antimicrobial agent recommendations to a backbone of high-dose cefazolin with or without metronidazole for most postinjury indications and recommendations for redosing of antimicrobial agents use of negative pressure wound therapy, and for oxygen supplementation in flight.


Descriptors :   *ANTIMICROBIAL AGENTS , *COMBAT AREAS , *INFECTIOUS DISEASES , *RESUSCITATION , *SURGERY , *TRAUMA , *WOUNDS AND INJURIES , CIVILIAN POPULATION , CLINICAL TRIALS , EXECUTIVE ROUTINES , IN VITRO ANALYSIS , INFLIGHT , OXYGEN , PRESSURE , PREVENTION , THERAPY , WARFARE


Subject Categories : Medicine and Medical Research
      Medical Facilities, Equipment and Supplies


Distribution Statement : APPROVED FOR PUBLIC RELEASE