Accession Number : ADA549706


Title :   Isolation, Expression Analysis, and Functional Characterization of the First Antidiuretic Hormone Receptor in Insects


Descriptive Note : Journal article


Corporate Author : DEPARTMENT OF AGRICULTURE COLLEGE STATION TX


Personal Author(s) : Paluzzi, Jean-Paul ; Park, Yoonseong ; Nachman, Ronald J ; Orchard, Ian


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a549706.pdf


Report Date : 01 Jun 2010


Pagination or Media Count : 7


Abstract : Diuresis following blood-gorging in Rhodnius prolixus is the major process leading to the transmission of Chagas disease. We have cloned the cDNA of the first receptor known to be involved in an antidiuretic strategy in insects, a strategy that prevents diuresis. This receptor belongs to the insect CAPA receptor family known in other insects to be activated by peptides encoded within the capability gene. We characterize the expression profile in fifthinstars and find expression is localized to the alimentary canal. Highest transcript levels are found in Malpighian tubules and the anterior midgut, which are known targets of the antidiuretic hormone, RhoprCAPA- 2.


Descriptors :   *INSECTS , ANTIDIURETICS , DISEASES , DIURESIS , FEEDING , HORMONES , PEPTIDES , RECEPTOR SITES(PHYSIOLOGY) , STRATEGY


Subject Categories : Biology


Distribution Statement : APPROVED FOR PUBLIC RELEASE