Accession Number : ADA548594


Title :   Imaging and Molecular Markers for Patients with Lung Cancer: Approaches with Molecular Targets, Complementary/Innovative Treatment, and Therapeutic Modalities


Descriptive Note : Annual rept. 1 Feb 2010-Jan 2011


Corporate Author : M D ANDERSON CANCER CENTER HOUSTON TX


Personal Author(s) : Hong, Waun K ; Herbst, Roy


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a548594.pdf


Report Date : Feb 2011


Pagination or Media Count : 113


Abstract : The projects in this proposal specifically target several signal transduction pathways known to be critical for NSCLC pathogenesis including the EGFR pathway and the more downstream ras/raf/Mek/ERK pathway. These projects combine targeted approaches using molecular and imaging techniques to validate activity against a target and monitor response using imaging modalities specific to the receptor using either small mole3cules or targeted peptide approaches.


Descriptors :   *LUNG CANCER , IMAGES , MARKERS , MOLECULES , PATHOGENESIS , PATIENTS , RESPONSE , SENSE ORGANS , SIGNALS , TARGETS , THERAPY , TRANSDUCERS


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE