Accession Number : ADA542260


Title :   Efficacy of Adjunct Sleep Interventions for PTSD (EASI-PTSD)


Descriptive Note : Annual rept. 17 Feb 2009-16 Feb 2010


Corporate Author : PITTSBURGH UNIV PA


Personal Author(s) : Germain, Anne ; Nofzinger, Eric A


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a542260.pdf


Report Date : Mar 2010


Pagination or Media Count : 69


Abstract : This is the final report for this study. We have completed all pre-and post assessment in all participants randomized to prazosin, placebo, or the behavioral sleep intervention. Two participants are currently completing the 4-month follow-up period. Data analysis for the acute treatment phase is currently underway, and the final analyses (which include 4-month follow-up data) will be initiated shortly. Recruitment has been more difficult than anticipated, but our enrollment rate (10% of individuals who completed the initial screening) is consistent with other ongoing studies in this population. Over the course of the performance period to date, this award has produced a number of reportable outcomes, including several scientific, peer-review presentations and symposia, and provided preliminary data for three successful applications for federal funding by the PI, Dr. Germain.


Descriptors :   *INTERVENTION , *SLEEP , PLACEBOS , POPULATION , RANDOM VARIABLES , DATA ACQUISITION


Subject Categories : Anatomy and Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE