Accession Number : ADA537599


Title :   An Implantable MEMS Drug Delivery Device for Rapid Delivery in Ambulatory Emergency Care


Descriptive Note : Journal article


Corporate Author : MASSACHUSETTS INST OF TECH CAMBRIDGE DEPT OF MATERIALS SCIENCE AND ENGINEERING


Personal Author(s) : Elman, N ; Duc, H H ; Cima, M


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a537599.pdf


Report Date : Jun 2009


Pagination or Media Count : 24


Abstract : We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD3 (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD3 provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD3 are proposed.


Descriptors :   *DRUGS , *MEDICAL SERVICES , *MICROELECTROMECHANICAL SYSTEMS , *EMERGENCIES , RESUSCITATION , AMBULANCES , IN VITRO ANALYSIS , TEST METHODS , HEART , DELIVERY


Subject Categories : Pharmacology
      Electrical and Electronic Equipment


Distribution Statement : APPROVED FOR PUBLIC RELEASE