Accession Number : ADA503219


Title :   Iron Deficiency and Obesity: The Contribution of Inflammation and Diminished Iron Absorption


Descriptive Note : Journal article


Corporate Author : ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA MILITARY NUTRITION DIV


Personal Author(s) : McClung, James P ; Karl, James P


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a503219.pdf


Report Date : Jan 2008


Pagination or Media Count : 6


Abstract : Poor iron status affects billions of people worldwide. The prevalence of obesity continues to rise in both developed and developing nations. An association between iron status and obesity has been described in children and adults. The mechanism explaining this relationship remains unknown; however, findings from recent reports suggest that body mass index and inflammation predict iron absorption and affect the response to iron fortification. The relationship between inflammation and iron absorption may be mediated by hepcidin, although further studies will be required to confirm this potential physiological explanation for the increased prevalence of iron deficiency in the obese.


Descriptors :   *NUTRITION , *OBESITY , *ABSORPTION , *INFLAMMATION , *CYTOKINES , *DEFICIENCIES , *IRON , WOMEN , ADULTS , EPIDEMIOLOGY , BODY WEIGHT , CHILDREN , THAILAND , MOROCCO , PUBLIC HEALTH , MEDICAL RESEARCH , RESPONSE(BIOLOGY) , PHYSIOLOGICAL EFFECTS , ADOLESCENTS , REPRINTS , DEVELOPING NATIONS , INDIA


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research
      Food, Food Service and Nutrition


Distribution Statement : APPROVED FOR PUBLIC RELEASE