Accession Number : ADA495492


Title :   VITAL (Vanguard Investigations of Therapeutic Approaches to Lung Cancer)


Descriptive Note : Annual rept. 15 Dec 2007-14 Dec 2008


Corporate Author : M D ANDERSON CANCER CENTER HOUSTON TX


Personal Author(s) : Hong, Waun K ; Lotan, Reuben ; Stewart, David


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a495492.pdf


Report Date : 01 Jan 2009


Pagination or Media Count : 309


Abstract : The VITAL Research Program will provide a better understanding of the cellular and molecular processes that drive lung tumorigenesis so that an accurate risk model for recurrence and/or the development of the secondary primary tumor can be developed, and the biologic agents most effective in reducing these events in the group of high-risk patients can be identified. We will be incorporating retrospective clinical trial specimens to develop our risk model and validating it with specimens collected from our Vanguard study. The research projects are proceeding well as proposed, producing valuable findings with cell lines, and will validate these results using the clinical samples obtained from the VITAL trials in the coming years.


Descriptors :   *LUNG CANCER , *CLINICAL MEDICINE , *PATIENTS , SAMPLING , CLINICAL TRIALS , CELLS(BIOLOGY) , INHALATION , CYTOLOGY , TOBACCO SMOKING , NEOPLASMS , RISK , BIOLOGICAL AGENTS , SURVIVAL(PERSONNEL)


Subject Categories : Personnel Management and Labor Relations
      Medicine and Medical Research
      Stress Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE