Accession Number : ADA483757


Title :   The Brain Tourniquet: Physiological Isolation of Brain Regions Damaged by Traumatic Head Injury


Descriptive Note : Final performance rept. Sep 2006-May 2008


Corporate Author : STATE UNIV OF NEW YORK DOWNSTATE MEDICAL CENTER BROOKLYN


Personal Author(s) : Ling, Douglas S F ; Yang, Lie ; Afroz, Sonia ; Hsieh, ChangChi


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a483757.pdf


Report Date : 19 Jun 2008


Pagination or Media Count : 22


Abstract : The objective of this study was to assess the feasibility of the brain tourniquet concept, a new therapeutic approach to battlefield traumatic brain injury (TBI). The purpose of the brain tourniquet is to physiologically isolate damaged brain regions in order to allow head-injured warfighters to remain combat effective after sustaining brain trauma. This will also enhance recovery from this type of injury by preventing the spread of damage into otherwise healthy brain tissue and extending the golden hour to reach comprehensive medical care. As such, the ultimate goal of the brain tourniquet is two-fold: 1) physiologically isolate injured brain regions to halt (or at least delay) the spread of neurological damage to uninjured brain areas, such as excitotoxicity, and 2) maintain or enhance normal physiological function in the intact, uninjured brain regions to preserve any remaining cognitive and motor function. This dual requirement is dictated by the unique demands of the battlefield environment, in which incapacitation of brain function renders the warfighter completely defenseless. The critical feature of this approach is that, if successful, it will enable head-injured soldiers to continue to function in the combat setting (i.e., for self-defense) until comprehensive medical care or medical evacuation can be effected.


Descriptors :   *MEDICAL SERVICES , *BRAIN , BATTLEFIELDS , ISOLATION , MEDICAL EVACUATION , NERVOUS SYSTEM , WOUNDS AND INJURIES , HEAD(ANATOMY) , TRAUMA , TISSUES(BIOLOGY) , WARFARE , THERAPY


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE