Accession Number : ADA435300


Title :   Cellular Effects of Enamel Matrix Derivative Are Associated With Specific Protein Components


Descriptive Note : Master's thesis


Corporate Author : AIR FORCE INST OF TECH WRIGHT-PATTERSONAFB OH


Personal Author(s) : Johnson, Dwight L


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a435300.pdf


Report Date : May 2005


Pagination or Media Count : 112


Abstract : Emdogain (trademark) or enamel matrix derivative (EMD), is a preparation of matrix proteins derived from developing porcine teeth. Although EMD has been shown to enhance both soft tissue healing and regeneration of the periodontium, the mechanism of this action is still unknown. It is assumed, but not yet proven, that amelogenin, the most abundant protein in EMD, is the protein primarily responsible for the effects of EMD. The purpose of this study was to fractionate EMD and associate specific cellular effects with specific protein components.


Descriptors :   *CELLS(BIOLOGY) , *TEETH , TISSUES(BIOLOGY) , PROTEINS , DISEASES , HEALING , SOFT TISSUES , REGENERATION(PHYSIOLOGY) , DENTAL ENAMEL


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE