Accession Number : ADA374099


Title :   Investigation of Seminal Plasma Hypersensitivity Reactions


Descriptive Note : Annual rept. 23 Sep 1997-22 Sep 1998 (Revised)


Corporate Author : CINCINNATI UNIV OH


Personal Author(s) : Bernstein, Jonathan


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a374099.pdf


Report Date : Oct 1998


Pagination or Media Count : 76


Abstract : Gulf War (GW)Veterans and/or their sexual partners have been-experiencing burning, pain and swelling of the urogenital tract after exposure to semen since returning from the Persian Gulf which has been referred to as Burning Semen Syndrome (BSS). The objectives of this research project are: (1) to identify the prevalence of BSS; (2) evaluate GW veterans and their sexual partners with BSS; (3) to determine if the underlying mechanism(s) of BSS is immunologic, infectious and/or toxicologic in nature; (4) to determine if the onset of BSS is related to chemical and/or biologic exposures encountered by GW veterans during their tour of duty in the Persian Gulf and; (5) to identify potential treatment(s) for BSS. The second year of this project has concentrated on obtaining completed questionnaires from the GW veteran and their spouse or sexual partner, obtaining screening laboratory tests to exclude an obvious underlying cause for their symptoms (i.e., sexually transmitted diseases), establishing the respective prevalence of BSS and localized/systemic seminal plasma protein hypersensitivity among the GW and civilian populations, obtaining body fluids from GW and civilian couples (sera and semen) to further investigate immunologic and infectious etiologies for their symptoms and finally, identification of control populations.


Descriptors :   *BODY FLUIDS , *GENITAL DISEASES , SIGNS AND SYMPTOMS , ETIOLOGY , ANTIBODIES , PAIN , IMMUNOLOGY , INFECTIOUS DISEASES , REPRODUCTIVE SYSTEM , SEX HORMONES , HYPERSENSITIVITY , PERSIAN GULF WAR


Subject Categories : Biochemistry
      Anatomy and Physiology
      Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE