Accession Number:

ADA352057

Title:

A Study of the Endogenous Control of Neuroinflammation, A Leading Cause of Morbidity from Traumatic Brain Injury

Descriptive Note:

Midterm rept. 23 Dec 96-30 Jun 98

Corporate Author:

UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD

Personal Author(s):

Report Date:

1998-07-01

Pagination or Media Count:

36.0

Abstract:

Neurotrauma constitutes 50 of combat related casualties. Among survivors, secondary injury contributes more to functional compromise than the primary traumatic event. A leading component of secondary injury is inflammation. Anti inflammatory therapy has not been exploited for central nervous system CNS injury because neuroinflammation is poorly understood. In this work, we provide the first in vivo demonstration of neuroinflammatory control.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE