Accession Number : ADA268153


Title :   Effects of Endotoxin Induced Lung Injury and Exercise in Goats/Sheep


Descriptive Note : Final rept. 1 Feb 92-2 Jun 93,


Corporate Author : TRIPLER ARMY MEDICAL CENTER HI


Personal Author(s) : Mundie, Thomas G


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a268153.pdf


Report Date : 02 Jun 1993


Pagination or Media Count : 23


Abstract : This study was designed the effects of exercise performed on animals already injured with E. coli endotoxin. This would tell us whether exercise makes the lung injury worse. It would also tell us how much exercise performance is impaired. These studies were designed to give further insights into the underlying causes of acute lung injury. Premature termination of the study prevented completion of the research project. It appeared from the limited experimentation conducted that maximal exercise was impaired by endotoxin- induced lung injury. Conclusions regarding exacerbation of endotoxin-induced lung injury cannot be made.


Descriptors :   *LUNG , *ENDOTOXINS , *EXERCISE(PHYSIOLOGY) , BIOLOGICAL AGENTS , ESCHERICHIA COLI , WOUNDS AND INJURIES , NITROGEN DIOXIDE , SHEEP , PULMONARY FUNCTION , GOATS , ANIMALS , CHEMICAL AGENTS


Subject Categories : Anatomy and Physiology
      Stress Physiology
      Pharmacology


Distribution Statement : APPROVED FOR PUBLIC RELEASE