Accession Number : ADA263938


Title :   Lead Exposures and Biological Responses in Military Weapons Systems: Aerosol Characteristics and Acute Lead Effects among U.S. Army Artilleryman - Final Report


Descriptive Note : Final rept. Jun 1986-Jul 1989


Corporate Author : ARGONNE NATIONAL LAB IL DIV OF BIOLOGICAL AND MEDICAL RESEARCH


Personal Author(s) : Bhattacharyya, M H ; Stebbings, J H ; Peterson, D P ; Johnson, S A ; Kumar, R


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a263938.pdf


Report Date : Mar 1993


Pagination or Media Count : 152


Abstract : This study was to determine the concentration and chemical nature of lead (Pb) aerosols produced during the firing of artillery and to determine the exposures and biological responses of crew members exposed to lead aerosols during such firing. The concentrations of lead-containing aerosols at crew positions depended on wind conditions, with higher concentrations when firing into a head wind. Aerosol concentrations were highest in the muzzle blast zone. Concentrations of lead in the blood of crew members rose during the first 12 days of exposure to elevated airborne lead concentrations and then leveled off. There was no rapid decrease in blood lead concentrations after completion of firing. Small decreases in hematocrit and small increases in free erythrocyte porphyrin were correlated with increasing exposure to airborne lead. These changes were reversed by seven weeks after firing. Changes in nerve conduction velocity had borderline statistical significance to airborne lead exposure. In measuring nerve conduction velocity, differences in skin temperature must be taken into account.


Descriptors :   *AEROSOLS , *LEAD COMPOUNDS , *EXPOSURE(PHYSIOLOGY) , *RESPONSE(BIOLOGY) , *ARTILLERY FIRE , *HOWITZERS , AIRBORNE , ERYTHROCYTES , HEAD(ANATOMY) , TANK CREWS , ARTILLERY , NERVES , BLOOD , SELF PROPELLED GUNS , HEMATOCRIT , PORPHYRINS , GUN CREWS


Subject Categories : Weapons Effects(biological)


Distribution Statement : APPROVED FOR PUBLIC RELEASE