Accession Number : ADA261917
Title : Development of Bioelastic Material for Aspects of Wound Repair.
Descriptive Note : Triannular progress rept. Sep-Dec 92.
Corporate Author : BIOELASTICS RESEARCH LTD BIRMINGHAM AL
Report Date : Jan 1992
Pagination or Media Count : 81
Abstract : The synthesis and characterization of bioelastic materials designed for specific applications of wound healing. For materials with possible use as wound coverings, control of the temperature of transition by changes in hydrophobicity will be examined. In addition, the rate of water passage through the matrix will be determined. The research approach is the stepwise coordination of the synthesis and characterization of the materials. The first application phase was concerned primarily with synthesis of the basic polypentapeptide poly(VPGVG) and the analog with L-alanine substituted in position 3, poly(VPAVG) and mole fraction combinations thereof to achieve elastomeric matrices of varying elastic moduli.
Descriptors : *COMPOSITE MATERIALS , *ELASTIC PROPERTIES , *BIOMEDICINE , *BIOLOGICAL PRODUCTS , BIOLOGY , SYNTHESIS , WATER , FABRICS , WOUNDS AND INJURIES , HYDROPHOBIC PROPERTIES , ALBUMINOIDS , ALANINES , HEALING , AMINO ACIDS , TRANSITIONS , TEMPERATURE CONTROL , ADHESION , PROTEINS , PEPTIDES , POLYMERS
Subject Categories : Biochemistry
Medical Facilities, Equipment and Supplies
Adhesives, Seals and Binders
Laminates and Composite Materials
Distribution Statement : APPROVED FOR PUBLIC RELEASE