Accession Number : ADA261711


Title :   Study of Nephropathia Epidemica (NE) in Sweden.


Descriptive Note : Final rept. 15 Nov 88-14 Nov 91,


Corporate Author : NATIONAL BACTERIOLOGICAL LAB STOCKHOLM (SWEDEN)


Personal Author(s) : Niklasson, Bo


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a261711.pdf


Report Date : 28 Jan 1993


Pagination or Media Count : 27


Abstract : A total of 3524 rodents collected in a HFRS endemic area of Sweden were tested for Puumala (PUU) virus infection (both viral antigen in lungs and specific antibodies in serum) by ELISA. The material included 2493 Clethrionomys glareolus, 620 C. rufocanus, 367 Microtus agrestis, 39 Myopus Schisticolor and 5 Apodemus flavicollis. C. glareolus was found to be the most important vector of PUU virus. Infection rate did correlate with population density over time but with a time lag of one year. In addition monoclonal antibodies to PUU virus were generated and used for characterisation of virus and development of new diagnostic techniques. Two epidemiological studies, one in Bashkirtostan (Russia) and one among military personnel in Sweden were also performed. Sequele post HFRS in man were investigated.... Epidemiology, Immunology, BD, Foreign, RAD I.


Descriptors :   *HEMORRHAGIC FEVERS , *MEDICAL RESEARCH , *EPIDEMIOLOGY , *SWEDEN , USSR , DENSITY , MILITARY PERSONNEL , FOREIGN , RATES , VIRUS DISEASES , ANTIGENS , POPULATION , LUNG , ANTIBODIES , IMMUNOLOGY , MONOCLONAL ANTIBODIES , RODENTS


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE