Accession Number : ADA256169


Title :   Evaluation of the Toxic Effects of a 90-Day Continuous Exposure of Rats to Water-In-Oil Hydraulic Fluid Emulsion.


Descriptive Note : Final rept. Jun 1990-May 1991,


Corporate Author : MANTECH ENVIRONMENTAL TECHNOLOGY INC DAYTON OH


Personal Author(s) : Kinkead, E R ; Wolfe, R E ; Bunger, S K ; Leahy, H L ; Kimmel, E C


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a256169.pdf


Report Date : Sep 1991


Pagination or Media Count : 27


Abstract : A water in oil emulsion is being used in submarines as a hydraulic fluid under high pressure conditions. Acute toxicity tests using this hydraulic fluid indicated minimal toxicity. A continuous 90-day inhalation study was initiated to determine the possible toxic hazard that might be encountered from continuous exposure to Naval personnel. The test animals were exposed to either 0.2 or 1.0 mg hydraulic fluid m3. No treatment related effects were noted in body weights, organ weights, or clinical chemistry parameters at the conclusion of the study. Histopathology examination of the test animals revealed no lesions related to exposure. Under conditions of this study, no undue health hazard would be expected from exposures of 1.0 mg hydraulic fluid/m3 or less. F-344 Rats, Hydraulic fluid, Inhalation, Oil-in-water, Water in oil.


Descriptors :   *TOXIC HAZARDS , *HYDRAULIC FLUIDS , *EMULSIONS , TEST AND EVALUATION , RATS , PARAMETERS , HEALTH , HIGH PRESSURE , HYDROCARBONS , PRESSURE , ANIMALS , LESIONS , HISTOPATHOLOGY , BODY WEIGHT , BODIES , SUBMARINES , OILS , HYDRAULICS , GENERATORS , PERSONNEL , INHALATION , FLUIDS , WEIGHT , CHEMISTRY , TOXICITY , WATER , NAVAL PERSONNEL , HAZARDS


Subject Categories : Toxicology
      Lubricants and Hydraulic Fluids


Distribution Statement : APPROVED FOR PUBLIC RELEASE