Accession Number : ADA255253


Title :   Rapid Detection of Mycobacteria in Patients with HIV Infection.


Descriptive Note : Annual rept. 15 Mar 1991-14 Mar 1992,


Corporate Author : ARMED FORCES INST OF PATHOLOGY WASHINGTON DC


Personal Author(s) : Patel, Rubina J


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a255253.pdf


Report Date : 30 Jun 1992


Pagination or Media Count : 21


Abstract : Mycobacterium avium and M. intracellular (also known as the M. avium complex or MAC) are the etiologic agents of the most common systemic bacterial infections in patients with the Acquired Immunodeficiency Syndrome (AIDS) (8, 13, 20, 30). Tuberculosis also remains a major health problem in urban areas in the U.S. as well as in developing countries. Although treatment for M. avium/M. intracellular infections is usually disappointing (20,30), effective chemotherapy is available for tuberculosis; however, efficient patient management and control of transmission (9) are comprised by inadequacies in current laboratory techniques resulting in a delay of six to eight weeks before a definitive diagnosis, i.e., demonstration and speciation of acid-fast bacilli (AFB) can be accomplished. the recent outbreak of drug-resistant tuberculosis makes the need for rapid identification even more acute.


Descriptors :   *HUMAN IMMUNODEFICIENCY VIRUSES , *ACQUIRED IMMUNE DEFICIENCY SYNDROME , *MYCOBACTERIUM TUBERCULOSIS , *MYCOBACTERIACEAE , DEOXYRIBONUCLEIC ACIDS , PROTECTIVE TREATMENTS


Subject Categories : Medicine and Medical Research
      Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE