Accession Number : ADA227977


Title :   The Comparison of Gemfibrozil and Lovastatin Therapy in Patients with High LDL and Low HDL Cholesterol Levels


Descriptive Note : Doctoral thesis


Corporate Author : AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH


Personal Author(s) : Barnett, Michael D


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a227977.pdf


Report Date : Aug 1990


Pagination or Media Count : 48


Abstract : Pharmacologic interventions in primary hypercholesteremia are usually considered after saturated fat restricted diet has failed to achieve an adequate control. The specific drug selected may be based, among other things, on its cholesterol lowering efficacy, ability to incidence of coronary heart disease (CHD), long term safety record, and cost. In addition, the individual patient lipoprotein profile and the established agents on specific profile components may be considered. Framingham, MRFIT, and epidemiological studies demonstrated that patients with increased low-density lipoprotein (LDL) cholesterol Clinics Trial showed that lowering elevated levels of LDL cholesterol significantly lowered the risk of CHD development.


Descriptors :   *PHARMACOLOGY , CORONARY DISEASE , SATURATION , COSTS , PROFILES , LIMITATIONS , CHOLESTEROL , LEVEL(QUANTITY) , THERAPY , LOW DENSITY , FATS , PATIENTS , DRUGS , DIET , INTERVENTION , LIPOPROTEINS , HEART , EPIDEMIOLOGY , RISK , CLINICAL MEDICINE


Subject Categories : Pharmacology


Distribution Statement : APPROVED FOR PUBLIC RELEASE