Accession Number : ADA222730


Title :   Dengue Fever in American Military Personnel in the Philippines: Clinical Observations on Hospitalized Patients during a 1984 Epidemic


Descriptive Note : Technical rept. Jun-Aug 1984


Corporate Author : NAVAL MEDICAL RESEARCH UNIT NO 2 DETACHMENT JAKARTA (INDONESIA)


Personal Author(s) : Hayes, C G ; O'Rourke, T F ; Fogelman, V ; Leavengood, D D ; Crow, G


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a222730.pdf


Report Date : Mar 1989


Pagination or Media Count : 11


Abstract : From June-Aug 1984, 24 American military personnel were hospitalized with dengue (DEN) at Clark Air Base in the Philippines. Their infections were confirmed by serology using the hemagglutination-inhibition test and/or by virus isolation in Aedes pseudoscutellaris cell cultures. Most of the patients had a secondary type of antibody response probably reflecting prior vaccination against yellow fever. Three serotypes of DEN virus were isolated; 7 isolates of DEN 1, 4 isolates of DEN 3 and 3 isolates of DEN 2. All of the patients were Caucasian males between the ages of 20-43 years. All of the cases were clinically diagnosed as classical dengue fever. A platelet count 100,000/ul was a common finding (83.3%); however, hemoconcentration was not documented. Other major findings were the occurrence of mild hypotension (62.5%) and petechiae (37.5%). One patient presented with shock and upper gastrointestinal bleeding, but his diagnosis was complicated by a history of epigastric pain and use of aspirin. Although all of the patients fully recovered, the severity of illness was clearly documented by the average-length of hospitalization (5.9 days) and average time absent from work (8.7 days). Keywords: Dengue fever, Clark air base, 1984 dengue epidemic, Philippines.


Descriptors :   *PATIENTS , *HOSPITALIZATIONS , *IMMUNIZATION , SECONDARY , ISOLATION , CLINICAL MEDICINE , CONCENTRATION(COMPOSITION) , ANTIBODIES , RESPONSE(BIOLOGY) , INFECTIOUS DISEASES , VIRUSES , CELLS(BIOLOGY) , AIRPORTS , SEROLOGY , ANTIGENS , CULTURES(BIOLOGY) , FEVERS , PHILIPPINES , VACCINES , DENGUE , HEMORRHAGE , GASTROINTESTINAL SYSTEM , BLOOD CELLS , AEDES , YELLOW FEVER , SALICYLIC ACIDS , MILITARY FACILITIES , HYPOTENSION , REPRINTS , MILITARY PERSONNEL


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE