Accession Number : ADA199154


Title :   Mutagenic Potential of Nitrosoguanidine in the Drosophila melanogaster Sex-Linked Recessive Lethal Test


Descriptive Note : Final rept.


Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA


Personal Author(s) : Gupta, Raj K ; Villa, Vilmar O ; Korte, Jr, Don W


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a199154.pdf


Report Date : Aug 1988


Pagination or Media Count : 27


Abstract : Nitrosoguanidine, an anticipated degradation product of nitroguanidine which in turn is a primary component of U.S. Army tripe-base propellants, was evaluated for mutagenic potential in the Drosophila melanogaster Sex-Linked Recessive Lethal test. Nitrosoguanidine was non- mutagenic following 72-hour feeding exposures to concentrations of nitrosoguanidine ranging from 5 mg/ml to 50 mg/ml. Keywords: Mutagenicity, Genetic toxicology.


Descriptors :   *MUTAGENS , *NITROGUANIDINE , *TOXICITY , LETHALITY , DROSOPHILA , GENETICS , SEX , TOXICOLOGY , DEGRADATION , TEST AND EVALUATION


Subject Categories : Toxicology
      Ammunition and Explosives


Distribution Statement : APPROVED FOR PUBLIC RELEASE