Accession Number : ADA199154
Title : Mutagenic Potential of Nitrosoguanidine in the Drosophila melanogaster Sex-Linked Recessive Lethal Test
Descriptive Note : Final rept.
Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
Personal Author(s) : Gupta, Raj K ; Villa, Vilmar O ; Korte, Jr, Don W
Report Date : Aug 1988
Pagination or Media Count : 27
Abstract : Nitrosoguanidine, an anticipated degradation product of nitroguanidine which in turn is a primary component of U.S. Army tripe-base propellants, was evaluated for mutagenic potential in the Drosophila melanogaster Sex-Linked Recessive Lethal test. Nitrosoguanidine was non- mutagenic following 72-hour feeding exposures to concentrations of nitrosoguanidine ranging from 5 mg/ml to 50 mg/ml. Keywords: Mutagenicity, Genetic toxicology.
Descriptors : *MUTAGENS , *NITROGUANIDINE , *TOXICITY , LETHALITY , DROSOPHILA , GENETICS , SEX , TOXICOLOGY , DEGRADATION , TEST AND EVALUATION
Subject Categories : Toxicology
Ammunition and Explosives
Distribution Statement : APPROVED FOR PUBLIC RELEASE