Accession Number : ADA153979


Title :   Studies to Control Endemic Typhoid Fever in Chile


Descriptive Note : Rept. no. 2 (Annual) 1 Jan-31 Dec 1982


Corporate Author : MARYLAND UNIV BALTIMORE CENTER FOR VACCINE DEVELOPMENT


Personal Author(s) : Levine, Myron M ; Black, Robert E ; Lanata, Claudio ; Clements, Mary L ; Sears, Stephen


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a153979.pdf


Report Date : 30 Jan 1983


Pagination or Media Count : 64


Abstract : A multi-faceted program of applied research was undertaken to control endemic typhoid fever in Santiago, Chile. These studies included: (1) A Case/Control study to identify risk factors and incriminate specific vehicles involved in transmission of S. typhi. (2) Prevalence of chronic S. typhi carriers in persons with cholecystitis. (3) Simple serologic and other screening tests to identify chronic S. typhi carriers. (4) A simple, practical, non- surgical treatment for chronic S. typhi carriers. (5) An evaluation of the sensitivity and specificity of diagnosing acute typhoid fever by identifying Vi antigen in urine. (6) A field-trial of Ty21a attenuated S. typhi vaccine. Keywords: Salmonellosis; Immunization; and Epidemiology, and Vi antigen.


Descriptors :   *IMMUNOLOGY , *EPIDEMIOLOGY , *FEVERS , *TYPHOID , DIAGNOSIS(MEDICINE) , SEROLOGY , ANTIGENS , IMMUNIZATION , VACCINES , SALMONELLOSIS , CHILE


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE