Accession Number : ADA152070


Title :   Design and Analysis of Chronic Aquatic Tests of Toxicity with Daphnia magna.


Descriptive Note : Final rept. 1 Nov 80-31 Dec 81,


Corporate Author : BATTELLE COLUMBUS LABS OH


Personal Author(s) : Feder,P I


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a152070.pdf


Report Date : Dec 1981


Pagination or Media Count : 465


Abstract : The investigation considers aspects of the summarization, graphical display, and statistical analysis of data arising from chronic aquatic tests of toxicity with Daphnia magna and statistical issues involved in the planning of such tests. All procedures are illustrated with examples based on real data. The report consists of fifteen sections. Section I describes the data and the toxicity tests from which they come. Sections II-VIII discuss and illustrate various preliminary data displays and statistical analyses including preliminary graphical displays, tests for beaker to beaker heterogeneity within treatment groups, adjustments to account for such beaker to beaker heterogeneity, outlier detection procedure, comparisons of average response levels in the water and solvent control groups, and the extent of association between length and reproduction responses. Originator-supplied keywords: Daphnia Magna; Chronic aquatic toxicity tests; Statistical analysis; Graphical data display; Tests of hypothesis; Confidence intervals; Dose response estimation; Multiple regression analysis; Computer programs; Experimental design; Outlier detection; Variance; Heterogeneity; and Adjustments.


Descriptors :   *TOXICITY , *DAPHNIA , COMPUTER PROGRAMS , EXPERIMENTAL DESIGN , GRAPHS , TEST METHODS , REGRESSION ANALYSIS , DOSAGE , HETEROGENEITY , DATA DISPLAYS , STATISTICAL ANALYSIS , HYPOTHESES , RESPONSE(BIOLOGY) , AQUATIC BIOLOGY , CONFIDENCE LIMITS


Subject Categories : Biology
      Toxicology


Distribution Statement : APPROVED FOR PUBLIC RELEASE