Accession Number : ADA148331


Title :   Mutagenic Potential of: 4-Nitrophenyl Dimethyl Phosphinate (TA007) using the Sex-Linked Recessive Lethal Test in Drosophila melanogaster.


Descriptive Note : Final rept. 10 Jan-6 Jun 83,


Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA


Personal Author(s) : Mauk,P D ; Powers,N R ; Mehr,Z A


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a148331.pdf


Report Date : Oct 1984


Pagination or Media Count : 29


Abstract : 4-Nitrophenyl dimethyl phosphinate (TA007) has a potential as a prophylactic agent in nerve agent poisoning. Mutagenic activity of this compound was assayed using the Sex-Linked Recessive Lethal test in Drosophila melanogaster. TA007 was determined to be non-mutagenic following 72-hour feeding exposures to 0.01 and 0.005 mM concentrations.


Descriptors :   *PHOSPHINATES , METHYL RADICALS , LETHALITY , MUTAGENS , PHENYL RADICALS , FEEDING , BIOASSAY , NITRO RADICALS , DROSOPHILA


Subject Categories : Toxicology


Distribution Statement : APPROVED FOR PUBLIC RELEASE