Accession Number : ADA148331
Title : Mutagenic Potential of: 4-Nitrophenyl Dimethyl Phosphinate (TA007) using the Sex-Linked Recessive Lethal Test in Drosophila melanogaster.
Descriptive Note : Final rept. 10 Jan-6 Jun 83,
Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
Personal Author(s) : Mauk,P D ; Powers,N R ; Mehr,Z A
Report Date : Oct 1984
Pagination or Media Count : 29
Abstract : 4-Nitrophenyl dimethyl phosphinate (TA007) has a potential as a prophylactic agent in nerve agent poisoning. Mutagenic activity of this compound was assayed using the Sex-Linked Recessive Lethal test in Drosophila melanogaster. TA007 was determined to be non-mutagenic following 72-hour feeding exposures to 0.01 and 0.005 mM concentrations.
Descriptors : *PHOSPHINATES , METHYL RADICALS , LETHALITY , MUTAGENS , PHENYL RADICALS , FEEDING , BIOASSAY , NITRO RADICALS , DROSOPHILA
Subject Categories : Toxicology
Distribution Statement : APPROVED FOR PUBLIC RELEASE