Accession Number : ADA142983


Title :   An Epidemiological Investigation of Hart Park and Turlock Viruses in California.


Descriptive Note : Doctoral thesis,


Corporate Author : AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH


Personal Author(s) : Kziazek,T G


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a142983.pdf


Report Date : Jan 1984


Pagination or Media Count : 223


Abstract : Turlock (TUR) and Hart Park (HP) viruses were repeatedly isolated from the mosquito Culex tarsails in California. Both viruses were found to replicate in Cx. tarsalis following parenteral inoculation. Once infected, Cx. tarsalis could transmit HP virus to blood droplets. Low titers of HP stock viruses did not allow efficient evaluation of infection of Cx. tarasalis by ingestion of the virus. Laboratory studies failed to demonstrate transovarial transmission of either virus from paranterally infected females to their progency. One isolation of HP virus was made from a male Cx. tarsalis collected in Kern County but the frequency of isolation (1/8848) was much less than that from female Cx. tarsalis (112/38,369). A combination of neutralization and indirect fluorescent antibody tests on sera collected in California from humans and a variety of domestic and feral animals showed that TUR virus infection was most prevalent in feral birds and horses and HP virus infection was prevalent in feral birds and domestic dogs.


Descriptors :   *VIRUSES , *EPIDEMIOLOGY , *CULEX , MATHEMATICAL MODELS , HUMANS , NEUTRALIZATION , ISOLATION , REGRESSION ANALYSIS , ANTIBODIES , CALIFORNIA , BLOOD SERUM , INOCULATION , VIRUS DISEASES , BIRDS , CHICKENS , DOGS , DISEASE VECTORS , HORSES , INFECTIOUS DISEASE TRANSMISSION , FLUORESCENT ANTIBODY TECHNIQUES , MOSQUITO BORNE DISEASES


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research
      Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE