Accession Number : ADA114919


Title :   Alcohol-Induced Physiological Displacements and Their Effects on Flight-Related Functions


Corporate Author : FEDERAL AVIATION ADMINISTRATION OKLAHOMA CITY OK CIVIL AEROMEDICAL INST


Personal Author(s) : Lategola, Michael T ; Lyne, Peggy J ; Burr, Mary J


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a114919.pdf


Report Date : Mar 1982


Pagination or Media Count : 22


Abstract : Tolerances of human subjects for orthostasis and physical work were determined at a simulated altitude of 3,048 m. Orthostasis was induced with a lower body negative pressure (LBNP) device and physical work was done on a pedal ergometer. Altitude was simulated in a hypobaric chamber. Tests were carried out under two experimental conditions: (1) after subjects drank an alcoholic beverage, or (ii) after subjects drank a placebo beverage (no alcohol). The alcoholic beverage produced blood alcohol concentrations (BAC's) of about 90 mg/ 100 ml of blood (90 mg percent). At altitude, arterial oxyhemoglobin saturation (HbO2) remained adequately compensated but was lower after alcohol than after placebo intake. Arithmetic and eye/hand coordination performances were both significantly decreased after school. Ergometry, after alcohol, was well tolerated despite some decreased cardiorespiratory efficiency. The LBNP applied around peak BAC at altitude was tolerated without subjectively adverse symptoms despite significant decreases in several cardiovascular parameters. Cardiovascular adequacy along with maintained plasma volume around peak BAC appeared to be temporarily protective against orthostatic incapacitation during LBNP. Reversal of this temporary orthostatic protection during BAC recession is possible.


Descriptors :   *ALCOHOL CONSUMPTION , HYPOBARIC CHAMBERS , REDUCTION , OXYGEN , FLIGHT , PHYSIOLOGICAL EFFECTS , HIGH ALTITUDE , RESPIRATION , HEART RATE , CARDIOVASCULAR SYSTEM , TOLERANCES(PHYSIOLOGY) , BLOOD , ALCOHOLS , BLOOD PRESSURE , SIMULATION , PILOTS


Subject Categories : Stress Physiology
      Toxicology


Distribution Statement : APPROVED FOR PUBLIC RELEASE