Accession Number : ADA101829


Title :   Evaluation of Selected Subacute Effects of the Nitrotoluene Group of Munitions Compounds on Fish and Potential Use in Aquatic Toxicity Evaluation.


Descriptive Note : Final rept. 1 Jan 80-31 Mar 81,


Corporate Author : TULANE UNIV NEW ORLEANS LA SCHOOL OF PUBLIC HEALTH AND TROPICAL MEDICINE


Personal Author(s) : Hartley,William Ralph


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a101829.pdf


Report Date : Mar 1981


Pagination or Media Count : 223


Abstract : Juvenile bluegills were exposed to 0.05 mg/L, 0.50 mg/L, 1.0 mg/L, 2.0 mg/L, 4.0 mg/L, 5.0 mg/L and 8.0 mg/L 2,4-DNT for eight weeks. Both first and second order growth constants indicated reduced growth rates with increasing 2,4-DNT concentration. The threshold concentration for significant growth rate reduction was 0.05 mg/L 2,4-DNT. No histological abnormalities were found in the digestive tract, pancreas, integument, heart, gonad, head kidney and spinal cord. Significant histopathological responses were observed in liver, spleen, trunk kidney, lateral line and gill in fish exposed to 0.5 mg/L - 8.0 mg/L 2,4-DNT for 45 - 56 days. The 2,4-DNT was rapidly absorbed (24-96 hours), reached relatively low bioconcentration levels and was rapidly eliminated (24-72 hours) when fish were placed in 2,4-DNT free environment. (Author)


Descriptors :   *TOXIC AGENTS , *EXPOSURE(PHYSIOLOGY) , *DNT , *OSTEICHTHYES , TISSUES(BIOLOGY) , LABORATORY TESTS , GROWTH(GENERAL) , PHYSIOLOGICAL EFFECTS , SPLEEN , LIVER DISEASES , BIOASSAY , CARDIOVASCULAR DISEASES , FISH GILLS , SUBLETHAL DOSAGE , KIDNEY DISEASES


Subject Categories : Anatomy and Physiology
      Toxicology
      Ammunition and Explosives


Distribution Statement : APPROVED FOR PUBLIC RELEASE