Accession Number : ADA052458


Title :   Prophylactic Methods in Prevention of Disease Among Army Personnel


Descriptive Note : Annual progress rept.


Corporate Author : LETTERMAN ARMY MEDICAL CENTER SAN FRANCISCO CA


Personal Author(s) : Smith, Creed D ; Stewart, Robert S ; Shiromoto, Ronald S ; Hull, Angus C


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/a052458.pdf


Report Date : Dec 1977


Pagination or Media Count : 50


Abstract : Surveillance studies to determine the etiologic agents of acute respiratory disease (ARD) in basic combat trainees (BCT's) were accomplished during FY 77. A special influenza surveillance program was also conducted at Forts Wood, Jackson and Bliss, to signal an early warning of a probable A/Swine flu epidemic. Virus isolations and Serological Studies indicated that 19.9% of ARD hospitalizations were caused by Adenoviruses, 4.5% by Influenza A and B, Mycoplasma, Coxsackie A 21 and Polio; and 74.7% by agents that were not determined. Field studies to determine the immunogenicity of Adenovirus Vaccines were conducted utilizing 360 serum pairs collected from 6 Training Forts. Accummulative results indicated the type 4 vaccine to be 69% immunogenic, and the type 7 was 63.6% immunogenic. A preliminary study to determine the effectiveness of Charcoal Viral Transport Media (CVTM), and bentonite media for transporting virus specimens was conducted using Tryptose Phosphate Broth (TPB) as a control. The recovery of Vaccinia, ECHO 9, Coxsackievirus, Polio, Adenovirus, Herpes, Mumps, and Influenza were similar, but neither media maintained virus titers as adequately as TPB. Studies to determine whether Coxsackievirus is a significant cause of upper-respiratory infections revealed that this agent represented 25%, 36/144, of the total number of viruses isolated during the period July thru December. Serological data confirms Coxsackievirus A21 as a significant cause of ARD.


Descriptors :   *TRAINEES , *PREVENTIVE MEDICINE , *MILITARY PERSONNEL , ADENOVIRUSES , URETHRITIS , COMMUNICABLE DISEASES , COXSACKIE VIRUS , GASTROENTERITIS , MENINGITIS , INFLUENZA VIRUS , IMMUNOLOGY , ESCHERICHIA COLI , VACCINES


Subject Categories : Personnel Management and Labor Relations


Distribution Statement : APPROVED FOR PUBLIC RELEASE