Accession Number : AD1049458


Title :   Enhancing Immune Checkpoint Inhibitor Therapy in Kidney Cancer


Descriptive Note : Technical Report,30 Sep 2016,29 Sep 2017


Corporate Author : University of Texas Southwestern Medical Center Dallas United States


Personal Author(s) : Hammers, Hans-Joerg


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1049458.pdf


Report Date : 01 Oct 2017


Pagination or Media Count : 5


Abstract : The purpose of this work is to develop strategies to enhance immune checkpoint inhibition in kidney cancer. The work is designed to test different strategies to induce or enhance the abscopal in a kidney cancer model by combining ablative techniques or TLR agonists with PD1 inhibitors. Funds were transferred to UT Southwestern mid 2017. The PI is in the process of getting IACUC/ACURO approval for the proposed animal studies.


Descriptors :   Immunotherapy , cancer , kidney diseases , inhibitors , therapy , radiotherapy , antibodies


Subject Categories : Medicine and Medical Research
      Pharmacology
      Biochemistry


Distribution Statement : APPROVED FOR PUBLIC RELEASE