Accession Number : AD1048448


Title :   Treating Gastrointestinal and Autism Symptoms in Adults with Autism Using Microbiota Transfer Therapy (MTT)


Descriptive Note : Technical Report,01 Sep 2016,31 Aug 2017


Corporate Author : Arizona State University Tempe United States


Personal Author(s) : Adams, James B


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1048448.pdf


Report Date : 01 Sep 2017


Pagination or Media Count : 18


Abstract : Purpose: The purpose of this study is to determine the safety and efficacy of Microbiota Transfer Therapy for adults with autism and chronic gastrointestinal problems. Scope: The scope of the project is a randomized, double-blind, placebo-controlled trial of MTT for 84 adults with autism. The trial also includes an extension, partial cross-over, and long-term follow-up (6, 12, and 18 months). It includes extensive evaluation of autism-related and gastrointestinal symptoms, evaluation of microbiome composition, and blood safety tests. It includes 84 neurotypical controls (half with GI symptoms, half without) for comparison of baseline microbiota (no treatment for the neurotypical group). Major findings: none to report yet.


Descriptors :   autism , gastrointestinal tract , constipation , diarrhea , transplants , clinical trials


Subject Categories : Medicine and Medical Research
      Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE